Prevalence of perianal intraepithelial neoplasia in HIV-infected patients referred for high-resolution anoscopy
Carcinoma in Situ
Carcinoma, Squamous Cell
Perianal disease was common in this group of HIV-infected patients; 11 patients (21 percent of total) were diagnosed with squamous-cell carcinoma or high-grade squamous intraepithelial lesion. Because only 19 patients had clinically suspicious perianal lesions biopsied, this may be an underestimate. Our data suggest that anal canal neoplasia often is accompanied by perianal disease and illustrates the need for biopsy of any suspicious perianal lesions.