An Update on Primary Central Nervous System Lymphoma Academic Article uri icon

Overview

MeSH Major

  • Central Nervous System Neoplasms
  • Lymphoma, Non-Hodgkin

abstract

  • The most important recent advance in treatment of primary central nervous system lymphoma has been the introduction of high-dose methotrexate-based chemotherapy. Convincing data demonstrate that the regimens of such chemotherapy improve survival compared with historical controls treated with radiotherapy alone. However, the optical treatment approach is still unclear and therapy can be associated with long-term neurotoxicity. Current research focuses on maximizing survival while minimizing neurologic sequelae.

publication date

  • December 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.hoc.2006.09.002

PubMed ID

  • 17113462

Additional Document Info

start page

  • 1267

end page

  • 85

volume

  • 20

number

  • 6