Diagnosis and treatment of chronic immune-mediated neuropathies Academic Article uri icon

Overview

MeSH Major

  • Amyotrophic Lateral Sclerosis
  • Mitochondrial Diseases
  • Nucleotidyltransferases
  • Oxidative Stress

abstract

  • The chronic autoimmune neuropathies are a diverse group of disorders, whose diagnosis and classification is based on the clinical presentations and results of ancillary tests. In chronic inflammatory demyelinating polyneuropathy, controlled therapeutic trials demonstrated efficacy for intravenous gamma-globulins, corticosteroids, and plasmaphereis. In multifocal motor neuropathy, intravenous gamma-globulins have been shown to be effective. In the other immune-mediated neuropathies, there are no reported controlled therapeutic trials, but efficacy has been reported for some treatments in non-controlled trials on case studies. Choice of therapy in individual cases is based on reported efficacy, as well as severity, progression, coexisting illness, predisposition to developing complications, and potential drug interactions.

publication date

  • March 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1097/01.cnd.0000205575.26451.e4

PubMed ID

  • 19078800

Additional Document Info

start page

  • 141

end page

  • 57

volume

  • 7

number

  • 3