High-risk African Americans with multiple risk factors for cardiovascular disease: Challenges in prevention, diagnosis, and treatment Review uri icon


MeSH Major

  • African Americans
  • Cardiovascular Diseases
  • Mass Screening


  • Coronary heart disease (CHD) is the second leading cause of death in the United States. Despite previous downward trends, which have not persisted, CHD mortality remains higher in African Americans than in Whites. Among African American and White adolescents and adults are trends of increased physical inactivity, smoking, and obesity. Approximately 47 million Americans have metabolic syndrome, a constellation of obesity, hypertension, dyslipidemia, and insulin resistance leading to diabetes. Despite a lower prevalence of metabolic syndrome, African Americans are more insulin resistant than Whites at similar degrees of adiposity, have higher blood pressures, and among women, have more obesity. Since African Americans tend to be diagnosed later and have more risk factors, which confers greater than additive risks, we propose the term "African American multiple-risk patient (AAMRP)." The AAMRP poses clinical and public health challenges for healthcare providers. We provide clinical and public health strategies for early detection and aggressive management of AAMRP.

publication date

  • December 2006



  • Review



  • eng

PubMed ID

  • 16937598

Additional Document Info

start page

  • 633

end page

  • 9


  • 16


  • 3