Somatic activation of KIT in distinct subtypes of melanoma Academic Article uri icon

Overview

MeSH Major

  • Biomarkers, Tumor
  • Melanoma
  • Proto-Oncogene Proteins c-kit
  • Skin Neoplasms

abstract

  • KIT is an important oncogene in melanoma. Because the majority of the KIT mutations we found in melanoma also occur in imatinib-responsive cancers of other types, imatinib may offer an immediate therapeutic benefit for a significant proportion of the global melanoma burden.

publication date

  • September 10, 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1200/JCO.2006.06.2984

PubMed ID

  • 16908931

Additional Document Info

start page

  • 4340

end page

  • 6

volume

  • 24

number

  • 26