Comment on "Large-scale sequence analysis of avian influenza isolates". Article Comment uri icon

Overview

MeSH Major

  • Antibodies, Monoclonal
  • Antigens, Neoplasm
  • Antineoplastic Agents
  • Cancer Vaccines
  • Immunotherapy
  • Melanoma

abstract

  • Obenauer et al. (Research Articles, 17 March 2006, p. 1576) reported that the influenza A virus PB1-F2 gene is evolving under strong positive selection, as documented by an extremely high ratio of the number of nonsynonymous nucleotide substitutions to the number of synonymous substitutions (dN/dS). However, we show that this observation is likely to be an artifact related to the location of PB1-F2 in the +1 reading frame of the PB1 gene.

publication date

  • September 15, 2006

Research

keywords

  • Comment

Identity

PubMed ID

  • 16973862

Additional Document Info

start page

  • 1573; author reply 1573

volume

  • 313

number

  • 5793