Angiogenic Profile of Soft Tissue Sarcomas Based on Analysis of Circulating Factors and Microarray Gene Expression Academic Article uri icon

Overview

MeSH Major

  • Angiopoietin-2
  • Fibroblast Growth Factors
  • Leptin
  • Neovascularization, Pathologic
  • Sarcoma
  • Vascular Endothelial Growth Factor A

abstract

  • STS demonstrate significant heterogeneity in their angiogenic profiles based on size, histologic subtype, and location of tumor growth, which may have implications for anti-angiogenic strategies. Comparison of STS to normal tissues reveals a panel of upregulated genes that may be targets for future therapies.

publication date

  • October 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.jss.2006.01.023

PubMed ID

  • 16603191

Additional Document Info

start page

  • 282

end page

  • 90

volume

  • 135

number

  • 2