Synergistic antitumor activity of taxol and immunotoxin SS1P in tumor-bearing mice Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Monoclonal
  • Antineoplastic Agents
  • Carcinoma
  • Paclitaxel

abstract

  • The combination of Taxol and SS1P exerts a synergistic antitumor effect in animals but not in cell culture. This effect is not secondary to increased tumor uptake of the immunotoxin. Synergy could be due to improved immunotoxin distribution within the tumor or could involve factors released by other cell types in the tumors.

publication date

  • August 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-06-0346

PubMed ID

  • 16899620

Additional Document Info

start page

  • 4695

end page

  • 701

volume

  • 12

number

  • 15