ADMA increases arterial stiffness and decreases cerebral blood flow in humans Academic Article uri icon

Overview

MeSH Major

  • Arginine
  • Cerebral Arteries
  • Cerebrovascular Circulation
  • Enzyme Inhibitors
  • Vasomotor System

abstract

  • Our results document for the first time that subpressor doses of ADMA increase vascular stiffness and decrease cerebral perfusion in healthy subjects. Thus, ADMA is an important endogenous modulator of cerebral vascular tone and may be involved in the pathogenesis of cerebrovascular disease.

publication date

  • August 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1161/01.STR.0000231640.32543.11

PubMed ID

  • 16809568

Additional Document Info

start page

  • 2024

end page

  • 9

volume

  • 37

number

  • 8