Poorly Differentiated Prostate Cancer Treated With Radical Prostatectomy: Long-Term Outcome and Incidence of Pathological Downgrading Academic Article uri icon

Overview

MeSH Major

  • Prostatectomy
  • Prostatic Neoplasms

abstract

  • Patients diagnosed with poorly differentiated prostate cancer (Gleason score 8 to 10) on biopsy do not uniformly have a poor prognosis. Of the patients 39% remain free of cancer recurrence 10 years after radical prostatectomy. Of these cancers 45% have a lower Gleason score in the radical prostatectomy specimen and a correspondingly more favorable long-term outcome. Predictors of downgrading are lower clinical stage (cT1c) and Gleason score 8 in the biopsy specimen.

publication date

  • September 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2239297

Digital Object Identifier (DOI)

  • 10.1016/j.juro.2006.04.048

PubMed ID

  • 16890678

Additional Document Info

start page

  • 991

end page

  • 5

volume

  • 176

number

  • 3