Impact of renal impairment on eligibility for adjuvant cisplatin-based chemotherapy in patients with urothelial carcinoma of the bladder Academic Article uri icon

Overview

MeSH Major

  • Chemotherapy, Adjuvant
  • Cisplatin
  • Eligibility Determination
  • Renal Insufficiency
  • Urethral Neoplasms
  • Urinary Bladder Neoplasms

abstract

  • : The widespread use of cisplatin-based perioperative chemotherapy in patients with high-risk localized bladder cancer may be significantly limited by the high prevalence of baseline renal insufficiency in this population. This finding is most striking in the elderly. Better selection of patients who may safely receive cisplatin and more effective regimens devoid of cisplatin are required to optimize outcomes in this group of patients.

publication date

  • August 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/cncr.22031

PubMed ID

  • 16773629

Additional Document Info

start page

  • 506

end page

  • 13

volume

  • 107

number

  • 3