Detection of the JAK2V617F mutation in myeloproliferative disorders by melting curve analysis using the lightcycler system Academic Article uri icon

Overview

MeSH Major

  • DNA Mutational Analysis
  • Molecular Diagnostic Techniques
  • Mutation
  • Myeloproliferative Disorders
  • Protein-Tyrosine Kinases
  • Proto-Oncogene Proteins

abstract

  • These findings demonstrate the suitability of this assay for identifying JAK2(V617F) in a clinical laboratory setting. Furthermore, the semiquantitative detection of JAK2(V617F) in archived specimens provides a new tool for studying the prognostic significance of this mutation.

publication date

  • July 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 16831057

Additional Document Info

start page

  • 997

end page

  • 1003

volume

  • 130

number

  • 7