Vaginal nitric oxide in pregnant women with bacterial vaginosis Academic Article uri icon

Overview

MeSH Major

  • Nitric Oxide
  • Vagina
  • Vaginosis, Bacterial

abstract

  • Elevated NO (>2.14 mmol/L) was associated with a diagnosis of BV (38% versus 11%, P < 0.008) as well as an increased median vaginal IL-1ra concentration (72.5 ng/ml versus 36.6 ng/ml, P = 0.041). Elevated vaginal NO was also associated with vaginal hsp70 and this relationship was independent of BV status or IL-1ra concentrations (P < 0.026). We conclude that vaginal hsp70 release in response to abnormal vaginal microflora may trigger NO production in an attempt to minimize the pathological consequences of this altered milieu.

publication date

  • August 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1111/j.1600-0897.2006.00388.x

PubMed ID

  • 16836610

Additional Document Info

start page

  • 86

end page

  • 90

volume

  • 56

number

  • 2