Safety and Efficacy of Intravesical Bacillus Calmette-Guerin Instillations in Steroid Treated and Immunocompromised Patients Academic Article uri icon

Overview

MeSH Major

  • Adjuvants, Immunologic
  • BCG Vaccine
  • Carcinoma in Situ
  • Immunocompromised Host
  • Steroids
  • Urinary Bladder Neoplasms

abstract

  • Intravesical bacillus Calmette-Guerin is a viable therapeutic option in patients with high risk superficial bladder cancer and concomitant lymphoma or chronic lymphocytic leukemia, treatment with low dose oral steroids or treatment with inhaled steroids. The bacillus Calmette-Guerin response rate at 6 months and the side effects profile associated with bacillus Calmette-Guerin therapy in these patients were comparable to those in patients with no evidence of immunosuppression. Further studies are warranted to assess the safety and efficacy of bacillus Calmette-Guerin instillations in critically immunocompromised patients.

publication date

  • August 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.juro.2006.03.066

PubMed ID

  • 16813873

Additional Document Info

start page

  • 482

end page

  • 5

volume

  • 176

number

  • 2