Transforming growth factor β signaling, vascular remodeling, and hypertension Academic Article uri icon

Overview

MeSH Major

  • Blood Pressure
  • Hypertension
  • Membrane Glycoproteins
  • Signal Transduction
  • Transforming Growth Factor beta

abstract

  • Mice deficient in Emilin1, an extracellular growth factor expressed in blood vessels, have hypertension. This observation, together with the finding that Emilin1 regulates the availability of transforming growth factor β (TGF-β), contributes to a growing body of evidence implicating TGF-β in hypertension. Copyright © 2006 Massachusetts Medical Society. All rights reserved.

publication date

  • June 22, 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1056/NEJMcibr062143

PubMed ID

  • 16790709

Additional Document Info

start page

  • 2721

end page

  • 3

volume

  • 354

number

  • 25