Expression of estrogen receptors-α and -β in bladder cancer cell lines and human bladder tumor tissue Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Transitional Cell
  • Estrogen Receptor alpha
  • Gene Expression Regulation, Neoplastic
  • Urinary Bladder Neoplasms

abstract

  • ERbeta is the dominant receptor expressed in bladder cancer cell lines and in the majority of human bladder tumors. Moreover, the degree of ERbeta expression increases with increasing stage and grade of differentiation. Antiestrogens have an inhibitory effect on the growth of bladder cancer cells in vitro.

publication date

  • June 15, 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/cncr.21945

PubMed ID

  • 16700038

Additional Document Info

start page

  • 2610

end page

  • 6

volume

  • 106

number

  • 12