Distribution of killer cell immunoglobulin-like receptors genotypes in the Lebanese population Academic Article uri icon

Overview

MeSH Major

  • Demography
  • Genotype
  • Receptors, Immunologic

abstract

  • This study represents the first report on the distribution of 16 Killer cell Immunoglobulin-like Receptors (KIR) genes in 120 unrelated healthy Lebanese individuals. We observed that 2DL2 frequency (61%) comes second highest after South Asians (64%) and 2DL5 frequency (58.3%) is the second highest reported so far after the South Asians (74%). Interestingly, a large number of AA1 genotype individuals with no loci for activating KIR and three completely new BB profiles not previously reported were found in our population with a group A : group B haplotypes ratio of 1.3:1. The frequency of the KIR loci suggests that the Lebanese population shares common general features with the Caucasoid populations studied before, but still has its own unique decreased or increased frequencies of several loci.

publication date

  • July 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1111/j.1399-0039.2006.00605.x

PubMed ID

  • 16774542

Additional Document Info

start page

  • 66

end page

  • 71

volume

  • 68

number

  • 1