Duration of adjuvant chemotherapy for colon cancer and survival among the elderly Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Colonic Neoplasms
  • Fluorouracil

abstract

  • More than 30% of elderly patients who initiated FU-based chemotherapy for stage III colon cancer and survived for at least 8 months discontinued treatment early. Mortality rates among such patients were nearly twice as high as among patients who completed 5 to 7 months of treatment. If the association we observed between duration of treatment and survival is confirmed, additional investigation is warranted to determine whether dose-intensity, cumulative dose, or other factors related to receipt of full adjuvant treatment are responsible.

publication date

  • May 20, 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1200/JCO.2005.04.5005

PubMed ID

  • 16618946

Additional Document Info

start page

  • 2368

end page

  • 75

volume

  • 24

number

  • 15