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Overview

MeSH Major

  • Antibodies, Monoclonal

abstract

  • Altogether, our data indicate that treatment of M14 melanoma cells with ATRA downregulates VnR expression and that this reduction is closely correlated with the ATRA-dependent inhibition of actin-fibre organization, cell adhesion and migration. Although the mechanism by which ATRA regulates the expression of VnR in M14 melanoma cells needs further elucidation, this system may represent a model for understanding the molecular basis of ATRA therapy in melanoma.

publication date

  • March 2006

Research

keywords

  • Letter

Identity

Digital Object Identifier (DOI)

  • 10.1016/j.jpeds.2006.01.023

Additional Document Info

start page

  • 424

end page

  • 33

volume

  • 148

number

  • 3