Visceral Leishmania donovani infection in interleukin-13-/- mice Academic Article uri icon

Overview

MeSH Major

  • Interleukin-13
  • Leishmania donovani
  • Leishmaniasis, Visceral

abstract

  • Leishmania donovani-infected interleukin-13-/- BALB/c mice showed impaired initial gamma interferon secretion and incomplete granuloma assembly at parasitized liver foci. Nonetheless, control of early parasite replication, resolution of liver infection, and responsiveness to antileishmanial chemotherapy were intact. By itself, interleukin-13 does not appear to materially influence acquired resistance in this intracellular infection.

publication date

  • April 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC1418934

Digital Object Identifier (DOI)

  • 10.1128/IAI.74.4.2487-2490.2006

PubMed ID

  • 16552085

Additional Document Info

start page

  • 2487

end page

  • 90

volume

  • 74

number

  • 4