Evaluation of 76Br-FBAU as a PET reporter probe for HSV1-tk gene expression imaging using mouse models of human glioma Academic Article uri icon

Overview

MeSH Major

  • Bromouracil
  • Gene Expression Profiling
  • Glioma
  • Thymidine Kinase
  • Transfection
  • Viral Proteins

abstract

  • (76)Br-FBAU accumulates in glioma cells constitutively expressing HSV1-tk by either adenoviral transduction or in stably expressing cell lines both in vitro and in vivo. (76)Br-FBAU shows promise as a PET reporter probe for use with the HSV1-tk in vivo gene expression imaging system.

publication date

  • November 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 16269608

Additional Document Info

start page

  • 1923

end page

  • 30

volume

  • 46

number

  • 11