Galectin-1: A link between tumor hypoxia and tumor immune privilege
Carcinoma, Squamous Cell
Head and Neck Neoplasms
Galectin-1 is a novel hypoxia-regulated protein and a prognostic marker in HNSCC. This study presents a new mechanism on how hypoxia can affect the malignant progression and therapeutic response of solid tumors by regulating the secretion of proteins that modulate immune privilege.