The Clinical Management of Clonal Hematopoiesis: Creation of a Clonal Hematopoiesis Clinic. Review uri icon

Overview

abstract

  • The acquisition of mutations in hematologic stem cells (clonal hematopoiesis) is common with normal aging and can be identified as an incidental finding through clinical genetic testing. Clonal hematopoiesis is associated with a heightened risk of developing hematologic neoplasms (especially myeloid) and accelerated atherosclerotic cardiovascular disease. This article discusses a multidisciplinary clinical approach to the management of patients with clonal hematopoiesis. Key areas of research needed to establish evidence-based clinical care guidelines and intervention strategies for individuals with clonal hematopoiesis are discussed.

publication date

  • January 18, 2020

Research

keywords

  • Clonal Hematopoiesis
  • Hematologic Diseases

Identity

Scopus Document Identifier

  • 85077928427

Digital Object Identifier (DOI)

  • 10.1016/j.hoc.2019.11.006

PubMed ID

  • 32089215

Additional Document Info

volume

  • 34

issue

  • 2