Tissue expression of transforming growth factor-β1 and its receptors: Correlation with pathologic features and biochemical progression in patients undergoing radical prostatectomy Academic Article uri icon

Overview

MeSH Major

  • Prostatic Neoplasms
  • Receptors, Transforming Growth Factor beta
  • Transforming Growth Factor beta

abstract

  • Our results showed that abnormal expression of TGF-beta1 and its receptors is common in prostate cancer. TGF-beta1 overexpression is moderately but significantly associated with a loss of expression of TGFbeta-RI and TGFbeta-RII. Loss of TGFbeta-RI expression is a prognostic marker in patients with prostate cancer.

publication date

  • June 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.urology.2003.12.015

PubMed ID

  • 15183988

Additional Document Info

start page

  • 1191

end page

  • 7

volume

  • 63

number

  • 6