Long-term functionality of cryopreserved parathyroid autografts: A 13-year prospective analysis Academic Article uri icon

Overview

MeSH Major

  • Cryopreservation
  • Hypoparathyroidism
  • Parathyroid Glands
  • Recovery of Function
  • Transplantation, Heterotopic

abstract

  • Based on these data and those in previous studies, approximately 60% of delayed, cryopreserved parathyroid autografts are functional. In this study 40% autografts (46% of patients) achieved full competency off supplements. Some patients have evidence of graft function with normal PTH levels but are not normocalcemic. Results were similar for patients with MEN and nonhereditary hyperparathyroidism. The duration of cryopreservation was a significant indicator of graft failure, and no functional autograft was observed beyond 22 months of preservation. CHPA is a useful treatment modality for patients with postoperative hypocalcemia after thyroid or parathyroid surgery, who do not respond to immediate parathyroid autotransplantation.

publication date

  • December 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.surg.2005.09.029

PubMed ID

  • 16360388

Additional Document Info

start page

  • 1033

end page

  • 40; discussion 1040-1

volume

  • 138

number

  • 6