Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: An overview of the randomised trials Report uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Carcinoma
  • Models, Theoretical
  • Neoplasm Staging

abstract

  • In these trials, avoidance of a local recurrence in the conserved breast after BCS and avoidance of a local recurrence elsewhere (eg, the chest wall or regional nodes) after mastectomy were of comparable relevance to 15-year breast cancer mortality. Differences in local treatment that substantially affect local recurrence rates would, in the hypothetical absence of any other causes of death, avoid about one breast cancer death over the next 15 years for every four local recurrences avoided, and should reduce 15-year overall mortality.

authors

publication date

  • December 17, 2005

Research

keywords

  • Report

Identity

Digital Object Identifier (DOI)

  • 10.1016/S0140-6736(05)67887-7

Additional Document Info

start page

  • 2087

end page

  • 106

volume

  • 366

number

  • 9503