Recognizing and monitoring adverse events of second-generation antipsychotics in children and adolescents Review uri icon

Overview

MeSH Major

  • Antipsychotic Agents
  • Mental Disorders
  • Recognition (Psychology)

abstract

  • Although second-generation antipsychotics (SGAs) are used increasingly in children and adolescents, data on the effectiveness and safety in pediatric populations are still sparse. Much of the safety information is derived from studies conducted in adults. This derivation is problematic because children and adolescents are exposed to SGAs during a phase of unparalleled physical and psychologic development that can affect pharmacokinetic and pharmacodynamic drug actions, efficacy, and side-effect patterns. This article presents an overview of SGA-related side effects in children and adolescents and strategies to monitor health outcomes effectively in youngsters receiving SGAs.

publication date

  • January 2006

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.chc.2005.08.007

PubMed ID

  • 16321730

Additional Document Info

start page

  • 177

end page

  • 206

volume

  • 15

number

  • 1