Aplidin reduces growth of anaplastic thyroid cancer xenografts and the expression of several angiogenic genes Academic Article uri icon

Overview

MeSH Major

  • Angiogenesis Inhibitors
  • Antineoplastic Agents
  • Carcinoma
  • Depsipeptides
  • Gene Expression Regulation, Neoplastic
  • Thyroid Neoplasms

abstract

  • This data supports the hypothesis that APLD may be an effective adjunctive therapy against ATC. The demonstrated molecular impact against angiogenic related genes specifically supports future strategies combining APLD with VEGF interacting agents.

publication date

  • January 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1007/s00280-005-0014-7

PubMed ID

  • 16001179

Additional Document Info

start page

  • 7

end page

  • 14

volume

  • 57

number

  • 1