Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors Academic Article uri icon

Overview

MeSH Major

  • Glioblastoma
  • PTEN Phosphohydrolase
  • Protein Kinase Inhibitors
  • Receptor, Epidermal Growth Factor

abstract

  • Coexpression of EGFRvIII and PTEN by glioblastoma cells is associated with responsiveness to EGFR kinase inhibitors.

publication date

  • November 10, 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1056/NEJMoa051918

PubMed ID

  • 16282176

Additional Document Info

start page

  • 2012

end page

  • 24

volume

  • 353

number

  • 19