Treatment of osteosarcoma at first recurrence after contemporary therapy: The memorial sloan-kettering cancer center experience
Neoplasm Recurrence, Local
At R1, 22 of 31 patients achieved a CR2 with aggressive surgery and chemotherapy. The majority of these patients subsequently developed a disease recurrence. Patients appeared to benefit from the addition of ifosfamide to their retrieval regimens. In the end, the role of chemotherapy in recurrent OS continues to remain undefined.