Identification of a novel 5-base pair deletion in calcineurin B (PPP3R1) promoter region and its association with left ventricular hypertrophy Academic Article uri icon

Overview

MeSH Major

  • Base Sequence
  • Calcineurin
  • Hypertrophy, Left Ventricular
  • Polymorphism, Genetic
  • Promoter Regions, Genetic
  • Sequence Deletion

abstract

  • The 5-base pair deletion within the CnB gene may cause excessive LV growth beyond the level appropriate for cardiac workload when exposed to severe hypertension or may be in linkage disequilibrium with the causal mutation.

publication date

  • October 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.ahj.2004.12.004

PubMed ID

  • 16209992

Additional Document Info

start page

  • 845

end page

  • 51

volume

  • 150

number

  • 4