Role of depression and inflammation in incident coronary heart disease events Review uri icon

Overview

MeSH Major

  • Coronary Disease
  • Depressive Disorder
  • Inflammation Mediators

abstract

  • Inflammatory biomarkers and depression have been proposed as novel coronary heart disease (CHD) risk markers. However, prospective studies have rarely assessed these 2 candidate CHD risk markers simultaneously in predicting incident CHD events. Therefore, although depression and elevated inflammatory biomarkers frequently covary, it is unclear how these risk markers relate to each other and to CHD event onset. The elucidation of these causal pathways has important clinical implications for patients who are depressed and/or have elevated inflammatory biomarkers. In this review, the publications examining the relations among depression, inflammation, and CHD events are discussed.

publication date

  • October 2005

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.amjcard.2005.05.064

PubMed ID

  • 16188535

Additional Document Info

start page

  • 1016

end page

  • 21

volume

  • 96

number

  • 7