Partial-breast radiation for early staged breast cancers: Hypothesis, existing data, and a planned phase III trial Review uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Radiotherapy

abstract

  • This review of clinical data from partial-breast treatment studies discusses results from a single institution's experience using brachytherapy catheters, the MammoSite balloon (Proxima Company, Alpharetta, GA), and three-dimensional external beam partial-breast treatment. Rationale, techniques, dose schedules, and available results are presented. Intra-operative single-dose radiation to the lumpectomy site is also reviewed. The National Surgical Adjuvant Breast and Bowel Project (NSABP) and Radiation Therapy Oncology Group (RTOG) cooperative groups are opening a phase III trial to compare partial-breast treatment to the standard 5- to 6-week course of whole-breast radiation. The design of this study is also presented in this review.

publication date

  • May 2005

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 16002002

Additional Document Info

start page

  • 301

end page

  • 7

volume

  • 3

number

  • 3