Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium
Fetal Tissue Transplantation
Pluripotent Stem Cells
Stem Cell Transplantation
In vivo differentiated ESCs elicit an accelerated immune response as compared with undifferentiated ESCs. These data imply that clinical transplantation of allogeneic ESCs or ESC derivatives for treatment of cardiac failure might require immunosuppressive therapy.