In vivo and in vitro studies on Anaplasma phagocytophilum infection of the myeloid cells of a patient with chronic myelogenous leukaemia and human granulocytic ehrlichiosis Academic Article Article uri icon

Overview

MeSH Major

  • Anti-HIV Agents
  • Atazanavir Sulfate
  • Bone Density
  • Dideoxynucleosides
  • HIV Infections
  • Kidney
  • Lamivudine
  • Lipids
  • RNA, Viral
  • Ritonavir

abstract

  • The superior growth in CML cells compared with HL-60 cells suggests that A phagocytophilum preferentially infects mature granulocytes. The higher infection rate of the patient's mature versus immature granulocytes before treatment and the minimal level of infection of the patient's bone marrow support this. It is possible that the primary site of infection in HGE is the peripheral mature granulocytic population.

publication date

  • May 2004

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1136/jcp.2003.011775

PubMed ID

  • 15113857

Additional Document Info

start page

  • 499

end page

  • 503

volume

  • 57

number

  • 5