An interventional magnetic resonance imaging technique for the molecular characterization of intraprostatic dynamic contrast enhancement Academic Article uri icon

Overview

MeSH Major

  • Magnetic Resonance Imaging
  • Prostatic Neoplasms

abstract

  • The biological characterization of an individual patient's tumor by noninvasive imaging will have an important role in cancer care and clinical research if the molecular processes that underlie the image data are known. Spatial heterogeneity in the dynamics of magnetic resonance imaging contrast enhancement (DCE-MRI) is hypothesized to reflect variations in tumor angiogenesis. Here we demonstrate the feasibility of precisely colocalizing DCE-MRI data with the genomic and proteomic profiles of underlying biopsy tissue using a novel MRI-guided biopsy technique in a patients with prostate cancer.

publication date

  • December 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3299492

PubMed ID

  • 15967127

Additional Document Info

start page

  • 63

end page

  • 6

volume

  • 4

number

  • 1