Prospective, randomized trial of the effect of antibody induction in simultaneous pancreas and kidney transplantation: Three-year results Academic Article uri icon

Overview

MeSH Major

  • Kidney Transplantation
  • Pancreas Transplantation

abstract

  • Tacrolimus, mycophenolate mofetil, and corticosteroids resulted in excellent safety and efficacy in SPK transplant recipients. Actual 3-year kidney survival was significantly better in the induction group; however, CMV viremia and CMV syndrome rates were significantly higher in the T-cell-depleting antibody group. African Americans demonstrated a significantly greater risk of acute rejection despite antibody induction. Decisions regarding the use of induction therapy must weigh the risk of kidney graft loss or rejection against the risk of infection.

publication date

  • April 27, 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 15114097

Additional Document Info

start page

  • 1269

end page

  • 75

volume

  • 77

number

  • 8