An Image Driven Systems Biology Approach for Neurodegenerative Disease Studies in the TSC-mTOR Pathway. Academic Article uri icon

Overview

abstract

  • In this brief paper we present an overview of the TSC-mTOR pathway and its importance in neurodegenerative disease (ND). We illustrate the influence of ND on dendritic spine morphology. Then we discuss some details of functional gene networks (FGN) and use this information to propose an image driven systems biology approach for the construction of a FGN for ND. We conclude on its importance and the prospective outcome of our study.

publication date

  • May 2, 2009

Identity

PubMed Central ID

  • PMC3171509

PubMed ID

  • 21922078