Systemic transforming growth factor-β1 gene therapy induces Foxp3+ regulatory cells, restores self-tolerance, and facilitates regeneration of beta cell function in overtly diabetic nonobese diabetic mice Conference Paper uri icon

Overview

MeSH Major

  • Dependovirus
  • Immunity, Innate
  • alpha 1-Antitrypsin

abstract

  • Our data demonstrate that systemic TGF-beta1 gene therapy blocks islet destructive autoimmunity, facilitates islet regeneration, and cures diabetes in diabetic NOD mice.

publication date

  • May 15, 2005

Research

keywords

  • Conference Paper

Identity

Digital Object Identifier (DOI)

  • 10.1097/01.TP.0000161223.54452.A2

Additional Document Info

start page

  • 1091

end page

  • 6

volume

  • 79

number

  • 9