Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesothelioma Academic Article uri icon

Overview

MeSH Major

  • Mesothelioma
  • Organoplatinum Compounds
  • Pleural Neoplasms

abstract

  • Intrapleural L-NDDP therapy in this patient population is feasible with significant but manageable toxicity. Although pathologic responses are highly encouraging, areas of mesothelioma that are not in direct communication with the pleural space will evade drug exposure and limit efficacy in some patients. The optimal role of intrapleural L-NDDP therapy currently remains to be determined.

publication date

  • December 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1200/JCO.2005.00.802

PubMed ID

  • 15908659

Additional Document Info

start page

  • 3495

end page

  • 501

volume

  • 23

number

  • 15