Frequency of SOX group B (SOX1, 2, 3) and ZIC2 antibodies in Turkish patients with small cell lung carcinoma and their correlation with clinical parameters Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Neoplasm
  • Autoantibodies
  • Carcinoma, Small Cell
  • DNA-Binding Proteins
  • HMGB Proteins
  • High Mobility Group Proteins
  • Lung Neoplasms
  • Transcription Factors

abstract

  • The frequent and stable presence of SOX Group B and/or ZIC2 antibodies in SCLC, but not in healthy individuals examined, indicates they are serological markers of SCLC. However, the correlation between known clinical parameters of less aggressive disease and seroreactivity suggests that these antibodies are indicators of better prognosis in SCLC and warrants further studies to clarify the nature of the underlying immune responses.

publication date

  • June 15, 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/cncr.21088

PubMed ID

  • 15880380

Additional Document Info

start page

  • 2575

end page

  • 83

volume

  • 103

number

  • 12