Differences in [99mTc]TRODAT-1 SPECT binding to dopamine transporters in patients with multiple system atrophy and Parkinson's disease Academic Article uri icon

Overview

MeSH Major

  • Membrane Glycoproteins
  • Membrane Transport Proteins
  • Multiple System Atrophy
  • Nerve Tissue Proteins
  • Organotechnetium Compounds
  • Parkinson Disease
  • Tropanes

abstract

  • Movement disorder patients could be differentiated from controls, but MSA and PD patients could not be easily differentiated from each other. As a group, MSA patients had significantly higher mean [99mTc]TRODAT-1 binding, particularly in the posterior putamen, compared with PD patients and significantly lower binding compared with controls. This may reflect different pathophysiological processes of the two neurodegenerative diseases.

publication date

  • March 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1007/s00259-004-1667-x

PubMed ID

  • 15791439

Additional Document Info

start page

  • 302

end page

  • 7

volume

  • 32

number

  • 3