Physical activity, health status and risk of hospitalization in patients with severe chronic obstructive pulmonary disease. Academic Article uri icon

Overview

abstract

  • BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a leading cause of death and 70% of the cost of COPD is due to hospitalizations. Self-reported daily physical activity and health status have been reported as predictors of a hospitalization in COPD but are not routinely assessed. OBJECTIVES: We tested the hypothesis that self-reported daily physical activity and health status assessed by a simple question were predictors of a hospitalization in a well-characterized cohort of patients with severe emphysema. METHODS: Investigators gathered daily physical activity and health status data assessed by a simple question in 597 patients with severe emphysema and tested the association of those patient-reported outcomes to the occurrence of a hospitalization in the following year. Multiple logistic regression analyses were used to determine predictors of hospitalization during the first 12 months after randomization. RESULTS: The two variables tested in the hypothesis were significant predictors of a hospitalization after adjusting for all univariable significant predictors: >2 h of physical activity per week had a protective effect [odds ratio (OR) 0.60; 95% confidence interval (95% CI) 0.41-0.88] and self-reported health status as fair or poor had a deleterious effect (OR 1.57; 95% CI 1.10-2.23). In addition, two other variables became significant in the multivariate model: total lung capacity (every 10% increase) had a protective effect (OR 0.88; 95% CI 0.78-0.99) and self-reported anxiety had a deleterious effect (OR 1.75; 95% CI 1.13-2.70). CONCLUSION: Self-reported daily physical activity and health status are independently associated with COPD hospitalizations. Our findings, assessed by simple questions, suggest the value of patient-reported outcomes in developing risk assessment tools that are easy to use.

publication date

  • March 16, 2010

Research

keywords

  • Exercise
  • Health Status
  • Hospitalization
  • Pulmonary Disease, Chronic Obstructive

Identity

PubMed Central ID

  • PMC2889264

Scopus Document Identifier

  • 77953776671

Digital Object Identifier (DOI)

  • 10.1159/000296504

PubMed ID

  • 20234126

Additional Document Info

volume

  • 80

issue

  • 1