Assessment of regional tumor hypoxia using 18F- fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4- methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models Academic Article uri icon

Overview

MeSH Major

  • Cell Hypoxia
  • Fluorodeoxyglucose F18
  • Misonidazole
  • Neoplasms
  • Organometallic Compounds
  • Positron-Emission Tomography
  • Radiopharmaceuticals
  • Thiosemicarbazones

abstract

  • The difference in behavior between the R3327-AT and FaDu tumor models suggests a tumor-specific dependence of Cu-ATSM uptake and retention under hypoxic conditions.

publication date

  • April 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.ijrobp.2004.12.057

PubMed ID

  • 15817355

Additional Document Info

start page

  • 1493

end page

  • 502

volume

  • 61

number

  • 5