Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: A highly lethal subset associated with poor chemoresponse Academic Article uri icon

Overview

MeSH Major

  • Bone Neoplasms
  • Genes, p16
  • Genes, p53
  • Oncogene Proteins, Fusion
  • Sarcoma, Ewing
  • Transcription Factors
  • Tumor Suppressor Protein p14ARF

abstract

  • Alterations in p53 or p16/p14ARF are found in a fourth of ES cases and define a subset with highly aggressive behavior and poor chemoresponse.

publication date

  • December 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1200/JCO.2005.02.081

PubMed ID

  • 15659501

Additional Document Info

start page

  • 548

end page

  • 58

volume

  • 23

number

  • 3