Mortality in individuals with severe deficiency of α1-antitrypsin: Findings from the National Heart, Lung, and Blood Institute Registry Academic Article uri icon

Overview

MeSH Major

  • alpha 1-Antitrypsin Deficiency

abstract

  • We conclude that severe AAT deficiency poses a significant threat to health, that severe airflow obstruction is a major determinant of mortality, and that liver and lung disease account for the excess mortality in affected individuals. These findings support current efforts to enhance diagnostic recognition and treatment of AAT-deficient individuals.

publication date

  • April 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1378/chest.127.4.1196

PubMed ID

  • 15821195

Additional Document Info

start page

  • 1196

end page

  • 204

volume

  • 127

number

  • 4