Synthesis and antitumor evaluation of benzoylphenylurea analogs Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Phenylurea Compounds

abstract

  • Novel series of benzoylphenylurea analogs 7-10 were prepared and evaluated for in vitro cytotoxic activity against a panel of eight different human cancer cell lines. A very interesting inhibition profile against BxPC3, Mia-Paca, and Hep2 cells with compound 10 has been observed. Compounds 8 and 9 showed the significant cytotoxicity in Hep2 cells. All cell lines were resistant to compound 7.

publication date

  • May 3, 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2004.02.019

PubMed ID

  • 15081011

Additional Document Info

start page

  • 2213

end page

  • 6

volume

  • 14

number

  • 9