Perivascular epithelioid cell tumor of the oral mucosa Academic Article uri icon

Overview

MeSH Major

  • Epithelioid Cells
  • Mouth Neoplasms
  • Soft Tissue Neoplasms

abstract

  • Perivascular epithelioid cell tumors (PEComas) are a family of tumors defined by the coexpression of melanocytic and muscle markers. Examples have been reported in many organs, soft tissues, and bone. Further expanding the list of locations, we report a case arising in the hard palate. Histologically, the tumor was composed of large elongated or epithelioid cells with granular cytoplasm. Immunohistochemically, tumor cells were positive for HMB-45, Melan A/MART-1, CD10, smooth muscle actin, desmin, and calponin. Ultrastructural examination revealed stage I melanosomes, thin filaments, and dense plaques. Recurrence has not been reported after 20 months. To our knowledge, this is the first detailed description of an intraoral PEComa.

publication date

  • May 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 15859645

Additional Document Info

start page

  • 690

end page

  • 3

volume

  • 129

number

  • 5