Prognostic impact of trisomies of chromosomes and 5 among children with acute lymphoblastic leukemia and high hyperdiploidy (> 50 chromosomes) Academic Article uri icon

Overview

MeSH Major

  • Chromosomes, Human, Pair 10
  • Chromosomes, Human, Pair 17
  • Chromosomes, Human, Pair 5
  • Diploidy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Trisomy

abstract

  • Trisomy of chromosomes 10 and 17 as well as modal chromosome number 54 to 58 identify subgroups of patients with high-hyperdiploid ALL who have a better outcome than high-hyperdiploid patients who lack these cytogenetic features. Trisomy of chromosome 5 confers poorer outcome among high-hyperdiploid patients.

publication date

  • May 2000

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10784628

Additional Document Info

start page

  • 1876

end page

  • 87

volume

  • 18

number

  • 9