Breast conservation therapy for invasive breast cancer in Ashkenazi women with BRCA gene founder mutations Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Founder Effect
  • Genes, BRCA1
  • Genes, Tumor Suppressor
  • Germ-Line Mutation
  • Jews
  • Mastectomy, Segmental

abstract

  • Women with BRCA founder mutations are at increased risk for breast cancer-related events after breast conservation. However, mutation status is not an independent predictor of survival and should not influence decisions regarding adjuvant therapy. The increased contralateral breast cancer risk in women heterozygous for BRCA mutations mandates careful surveillance.

publication date

  • December 15, 1999

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10601383

Additional Document Info

start page

  • 2112

end page

  • 7

volume

  • 91

number

  • 24